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Capabilities

R&D, Pilot & Scale-Up

R&D facility setup, pilot plant engineering and scale-up — the R&D-to-production bridge. Our work serves the journey from laboratory discovery through pilot validation to commercial scale, covering facility engineering, regulatory coordination and pilot-to-commercial scale-up.

CapabilitiesOperating ExperienceEngagement Shapes
Capabilities

Each capability is named, scoped and tied to a deliverable.

R&D Centre Facility Engineering

Direct

Lab layout and zoning, fume hood and biosafety cabinet specifications, lab utility design (DI water, vacuum, compressed air, specialty gases) and HVAC for analytical and microbiology areas.

Deliverable received
OutputR&D centre facility design with layout, utilities and HVAC.

Kilo-Lab Setup

Direct

Process development at 100g to 10kg scale, the glovebox vs. open-bench decision, vent and scrubber engineering and hazardous chemical storage.

Deliverable received
OutputKilo-lab setup design with vent, scrubber and storage engineering.

Analytical Lab Engineering

Direct

Instrument lab utilities, HVAC for sensitive instruments, balance rooms, sample storage and waste handling.

Deliverable received
OutputAnalytical lab engineering with utilities, HVAC and sample handling.

Lab HVAC & Cleanroom Design

Direct

HVAC for analytical, microbiology, sterile and cleanroom areas, with pressure cascade design, filter selection (HEPA, ULPA) and particulate and microbial classification compliance.

Deliverable received
OutputLab HVAC and cleanroom design with pressure cascade and filtration.

R&D Regulatory Coordination

Coordination

Regulatory submissions — SPCB (CTE/CTO), Factory Inspectorate, CDSCO where applicable, and local Fire and Electrical authority approvals.

Deliverable received
OutputRegulatory submission package coordinated across the relevant authorities.

Pilot Plant Engineering

Direct

Pilot plant at 50L to 1000L reactor scale, with reactor configuration, distillation, filtration and drying integration and scale-up parameter capture.

Deliverable received
OutputPilot plant design with integrated unit operations and parameter capture.

Pilot-to-Commercial Bridge Engineering

Direct

Engineering review of pilot data to inform commercial-scale design, with equipment selection at commercial scale and mixing, heat transfer and mass transfer scale-up.

Deliverable received
OutputCommercial-scale design informed by reviewed pilot data.

Process Safety Scale-Up Studies

Direct

Reaction calorimetry interpretation, runaway scenario analysis at commercial scale and relief sizing for commercial equipment.

Deliverable received
OutputProcess safety scale-up study with runaway analysis and relief sizing.

Tech Transfer Engineering Support

Direct

Tech transfer between sites — common when products move from CDMO to internal manufacturing, or between plants of the same company.

Deliverable received
OutputTech transfer engineering support across sites.
Operating Experience

Direct engineering experience setting up R&D centres and pilot plants for growing API and fine chemical manufacturers. Process safety scale-up engineering across multiple commercial commissionings.

Typical Engagement Shapes

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